ABSTRACT
From January 1990 to December 1999 six isolates of Listeria monocytogenes were recovered in Casablanca from blood and / or CSF from 5 neonates and one three years old child. These isolates were studied by serotyping, phage typing and pulsed field gel electrophoresis. Resistance to 10 antibiotics was determined by E test method . All the isolates belong to serotype 1/2 b, except one serotype 4b. All the isolates were phage untypable. Four profiles were obtained by pulsed field gel electrophoresis . All the isolates were susceptible to penicillin G, ampicillin , gentamycin , rifampin and cotrimoxazole . One isolate [serotype 1/2b] was resistant to tetracycline [CMI > 256 mg/L] and one isolate [serotype 4b] was multiresistant [erythromycin MIC = 8 mcg/ml, chloramphenicol MIC > 256 mg/L and tetracycline MIC > 256 mg/L]. These results confirm the interest of DNA based techniques for typing sporadic isolates and stress the need for continuous surveillance of antibiotic resistance since multiresistance may occur
ABSTRACT
Between January 1988 and December 1991. A study about 10 cases of E. Coli K1 neonates infection was taken. This study find high data of mortality and morbidity. We assure that rapid diagnosis is an important test
Subject(s)
Humans , Infections , Infant, Newborn, Diseases , Escherichia coli Infections/drug therapy , Retrospective Studies , Escherichia coliABSTRACT
Authors report a case of salmonella typhi meningitis observed in the unity of intensive care of Casablanca Children Hospital. It is a rare affection with a dreadful prognostic especially occurring in infancy. Clinical, bacteriological aspects and the difficulty of treatment choice are reviewed
Subject(s)
Humans , Male , Salmonella typhi/pathogenicity , InfantABSTRACT
The authors report on a case of neonatal meningitis caused by a strain of E. coli K1. The interest of rapid technics for detection of bacterial antigens is emphasized and the place of third generation cephalosporins discussed
Subject(s)
Humans , Male , Infant, Newborn , Meningitis, Escherichia coli/drug therapy , CephalosporinsABSTRACT
Four strains of Listeria monocytogenes have been isolated from environnemental sources and feces from immunocompromised patients. These strains belong to the most frequent serotypes reported in human listeriosis, and are suceptible to various antibiotics
Subject(s)
Humans , Female , Listeria monocytogenes , Listeria , Pregnancy , Immunocompromised Host , Prospective StudiesABSTRACT
Serotype b correspond to 99% of the strains of II. influenzae isolated in meningitis. The biotypes I and II are the most frequent. The authors report on the first betalactame producing strain isolated in Morocco
Subject(s)
Humans , Meningitis , Haemophilus influenzae type b , beta-Lactamases , Ampicillin Resistance , Microbial Sensitivity TestsABSTRACT
The clinical and radiologic data cannot always differentiate between upper urinary tract and lower tract infections. The antibody coated bacteria test has been performed in 12 cases and has proved to be a sensitive and specific indicator of renal infection
Subject(s)
Humans , Male , Female , Urinary Tract Infections/immunology , Antibodies , Bacterial Infections/diagnosisABSTRACT
Several antibiotics have been recently marketed in Morocco. The authors evaluate their respective interests, and bring practical propositions for their use
Subject(s)
Hospitals, Teaching , Prospective Studies , Carbenicillin , Tobramycin , Netilmicin , Amikacin , Cefamandole , CefotaximeABSTRACT
The authors have used a simple and cheap microbiological method for the determination of the aminoglycoside serum levels of four patients. The clinical situation where these monitoring may be useful are emphasized
Subject(s)
Humans , Male , Female , Communicable Diseases/drug therapy , Endocarditis , Mitral Valve Insufficiency , Tuberculosis, Lymph Node , Peritonitis , Respiratory Tract Infections , Urinary Tract Infections , ComaABSTRACT
The authors report on the successful treatment of multiresistant klebsiella pneumoniae meningitis by cefotaxime. Because of their high antibacterial activity and their adequate diffusion into the cerebrospinal fluid, the "third generation cephalosporins" are suitable for treatment of gram negative meningitis
Subject(s)
Humans , Male , Klebsiella , Drug Resistance, Multiple, Bacterial , Cefotaxime , Klebsiella pneumoniae/drug effectsABSTRACT
Rotavirus have been demonstrated in 17.6% of stools of 85 children suffering from acute diarrhea. The low incidence reported here can be explained by the season and by the age of the children
Subject(s)
Humans , Rotavirus/pathogenicity , Infant , Child , Diarrhea/epidemiology , IncidenceABSTRACT
According to the data obtained from the second semester of 1983, the cytobacteriologic examinations of the urines represent one third of the total specimens received in the laboratory. 16.8% of the specimens analysed show a significant bacteriuria. The distribution of the bacteria and their antibiotic suceptibility are discussed
Subject(s)
Urinary Tract Infections/microbiology , Microbial Sensitivity Tests , Bacteriuria , Urine , Laboratories, Hospital , Retrospective StudiesABSTRACT
Antibiotic treatment of urinary tract infections is based upon natural history and clinical signs of the infection. The epidemiological, the bacteriological and pharmacological data are reviewed and the treatment of the major clinical situations is discussed
Subject(s)
Humans , Cystitis/drug therapy , Acute Disease , Chronic Disease , Pyelonephritis/drug therapy , Pregnancy , Prostatitis/drug therapy , Anti-Bacterial AgentsABSTRACT
Twenty nine patients with Gram negative urinary tract infection have received gentamicin in a single daily dose of 2,5 mg per kilogram of body weight for 10 days. Follow up is based on bacteriologic and biologic data and on dosage of gentamicin. The mean values of gentamicin levels obtained in blood and urine are efficient and non toxic. In 14% of cases, failure of treatment is due to a local cause of urinary tract infection. A single daily dose of gentamicin is efficient and non toxic if adapted to the patient's weight
Subject(s)
Humans , Gentamicins , Gentamicins/administration & dosage , Dose-Response Relationship, DrugABSTRACT
155 samples of cerebrospinal fluids have been tested by countercurrent timmunoelectrophoresis and by conventional bacteriology. Direct examination and culture of the samples were positive in 48.5% of cases, CIE detected the antigens in 63.5% and the combination of the 2 methods leaves only the 22.6% of the cases without known etiology. CIE have been also useful for grouping and typing bacterial antigens and for estimating the quantity of bacterial antigens in CSF. CIE is technically simple and provides results within 1 hour. Routinely it must be reserved to samples with negative direct examination
Subject(s)
ImmunoelectrophoresisABSTRACT
Using a microbiological method the authors have studied there is a prevalence of rapid acetylors, and this result agree with those of the 2 previous studies realised in Morocco. These results also show that the standard dosage of isoniazid used in Morocco has to be reduced, because no more than 5% of the 200 patients need a dosage higher than 9 mg /kg/day